Anda belum login :: 03 Oct 2022 16:02 WIB
Detail
ArtikelZygosity and chorionicity in triplet pregnancies: new data  
Oleh: Guilherme, Romain ; Drunat, Severine ; Delezoide, Anne-lise ; Oury, Jean-François ; Luton, Dominique
Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Human Reproduction vol. 24 no. 01 (Jan. 2009), page 100.
Topik: zygosity; chorionicity; triplets; microsatellites; assisted reproduction technologies
Ketersediaan
  • Perpustakaan FK
    • Nomor Panggil: H07.K.2009.01
    • Non-tandon: 1 (dapat dipinjam: 0)
    • Tandon: tidak ada
    Lihat Detail Induk
Isi artikelBACKGROUND: In studies of twin and triplet pregnancies, molecular genetic techniques have rarely been used to confirm zygosity yet this is the most accurate approach. The aim of this study was to present the cross-distribution of chorionicity and zygosity in triplet pregnancies as a function of their mode of conception using such techniques. Rates of monozygosity were studied simultaneously. METHODS: Forty-nine consecutive sets of triplets were observed in the study, including 18 sets of spontaneously conceived (SC) triplet pregnancies and 31 sets resulting from assisted reproduction technologies (ARTs). Zygosity was determined through PCR-amplified microsatellite analysis. Chorionicity was determined by placental analysis in our department of fetopathology. Sets of triplets were considered as twin pairs in order to determine the rate of monozygosity. RESULTS: For SC triplet pregnancies, the rate of monozygotic (MZ) twin pairs was 48%; 30% of dichorionic (DC) triplet pregnancies were MZ and 70% dizygotic (DZ); 20% of trichorionic (TC) triplet pregnancies were DZ and 80% trizygotic (TZ). For triplet pregnancies conceived using ART, the rate of MZ twin pairs was 6.5%; 100% of DC triplet pregnancies were DZ; 4% of TC triplet pregnancies were DZ and 96% TZ. CONCLUSIONS: This study is the first report to present the cross-distribution of chorionicity and zygosity in triplet pregnancies as a function of their mode of conception. In triplet pregnancies conceived using ART, DC triplets are always DZ, and TC triplets are almost always TZ.
Opini AndaKlik untuk menuliskan opini Anda tentang koleksi ini!

Kembali
design
 
Process time: 0.0156264 second(s)