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BukuComparison of the Effects of Walking and Bench-Step Exercise on Osteocalcin and CTX-1 in Post-Menopausal Women with Osteopenia (article of Journal of Musculoskeletal Research Vol.20 No.02 1750012 2017)
Author: Haryono, Ignatio Rika ; Tulaar, Angela ; Sudoyo, Herawati ; Purba, Ambrosius ; Abdullah, Murdani ; Jusman, Sri Widia A. ; Lubis, Andri M.T. ; Ilyas, Ermita I. Ibrahim
Topik: Bone formation; Bone resorption; Mechanical stimuli; JABFUNG-FKIK-IRH-2021-03
Bahasa: (EN )    
Penerbit: World Scientific Publishing Co Pte Ltd     Tempat Terbit: Singapore    Tahun Terbit: 2017    
Jenis: Article - diterbitkan di jurnal ilmiah internasional
Fulltext: B-3 Dokumen.pdf (156.74KB; 1 download)
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Purpose: Bench-step exercise produces biomechanical movements beneficial to improve bone remodeling. However, no studies have confirmed the effects of bench-step exercise (BE) on bone formation and resorption. The goal of this study is to compare the effects of bench-step and walking exercise (WE) on changes in osteocalcin and CTX-1 levels. Methods: Fifty-nine sedentary post-menopausal women with osteopenia (T-score between -1 and -2.5) were randomly divided into two groups: WE group (n=29) and BE group (n=30). Subjects performed 12 weeks of exercise. The osteocalcin and CTX-1 levels were analyzed using enzyme-linked immunosorbent assay. Independent t-test or Wilcoxon test was used to analyze the osteocalcin and CTX-1 levels. The difference in changes in the osteocalcin and CTX-1 between the groups before and after was analyzed using Mann–Whitney test. Results: The results showed a significant increase in the osteocalcin and CTX-1 levels in both groups (P<0.05). The increased levels of osteocalcin between groups were not statistically different (P>0.367). The increase in CTX-1 resulting from BE was lower than that from WE (P<0.048). Conclusion: This study indicates that BE may inhibit resorption stronger than WE.
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