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Comparison of the Effects of Walking and Bench-Step Exercise on Osteocalcin and CTX-1 in Post-Menopausal Women with Osteopenia (article of Journal of Musculoskeletal Research Vol.20 No.02 1750012 2017)
Haryono, Ignatio Rika
Jusman, Sri Widia A.
Lubis, Andri M.T.
Ilyas, Ermita I. Ibrahim
World Scientific Publishing Co Pte Ltd
Article - diterbitkan di jurnal ilmiah internasional
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Purpose: Bench-step exercise produces biomechanical movements beneficial to improve bone remodeling. However, no studies have confirmed the effects of bench-step exercise (BE) on bone formation and resorption. The goal of this study is to compare the effects of bench-step and walking exercise (WE) on changes in osteocalcin and CTX-1 levels. Methods: Fifty-nine sedentary post-menopausal women with osteopenia (T-score between -1 and -2.5) were randomly divided into two groups: WE group (n=29) and BE group (n=30). Subjects performed 12 weeks of exercise. The osteocalcin and CTX-1 levels were analyzed using enzyme-linked immunosorbent assay. Independent t-test or Wilcoxon test was used to analyze the osteocalcin and CTX-1 levels. The difference in changes in the osteocalcin and CTX-1 between the groups before and after was analyzed using Mann–Whitney test. Results: The results showed a significant increase in the osteocalcin and CTX-1 levels in both groups (P<0.05). The increased levels of osteocalcin between groups were not statistically different (P>0.367). The increase in CTX-1 resulting from BE was lower than that from WE (P<0.048). Conclusion: This study indicates that BE may inhibit resorption stronger than WE.
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