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Efektifitas Ekstrak Etanol Daun Afrika (Vernonia amygdalina) terhadap Penyembuhan Luka Bakar Derajat II Pada Tikus Putih Wistar
MEIDIANTO, SISILIA ANGELINA
Tanjung, Julia Rahadian
Wahyuningsih, Komang Ardi
BURNS AND SCALDS-TREATMENT
Fakultas Kedokteran Unika Atma Jaya
Theses - Karya Tulis Ilmiah Kedokteran (KTI-FK)
KTI Sisilia Angelina Meidianto (2014060160).pdf
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Background: Burns are a fairly common injury. The percentage of burn incidence was dominated by degree II (deep partial-thickness) burns of 73%. Treatment of
African leaves (Vernonia amygdalina) is thought to have a healing effect on burns. This leaf is easy to obtain and has antioxidant content, and also anti-inflammatory
that plays a role in healing burns.
Methods: This was experimental study. Samples were male wistar rats treated with burns, then given African ethanol leaves extract at dose of 180 mg/ml for 21 days. The wound size reduction was analyzed on days 3,7,14, and 21. Application to measure burn’s area was image J.
Results: There were significant differences on day 3 between African leave’s extract group compared with MEBO (P=0.016). On the 21st day there was a significant difference between the African leave’s extract group and the negative control group (P=0.009), then between the MEBO group compared with the negative control group (P=0.009) there were also significant differences.
Conclusion: African leave’s extract has a healing effect on burns. African leave’s extract has the same quality with MEBO ointment.
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