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BukuEfektifitas vaksin bivalen Human Papillomavirus terhadap pencegahan kanker serviks pada wanita yang belum dan sudah berhubungan seksual
Bibliografi
Author: Daniel ; Budhijuwono, Ardhito ; Lilis (Advisor); Simon, Sumanto (Advisor); Arieselia, Zita (Advisor)
Topik: SEXUALLY INTERCOURSE; HPV; cervical cancer; bivalent vaccine; kanker serviks; vaksin bivalen; hubungan seksual HPV; cervical cancer; bivalent vaccine; sexually intercourse
Bahasa: (ID )    
Penerbit: Fakultas Kedokteran Unika Atma Jaya     Tempat Terbit: Jakarta Utara    Tahun Terbit: 2011    
Jenis: Theses - Karya Tulis Ilmiah Kedokteran (KTI-FK)
Fulltext: Daniel_&_Ardhito_KTI_2011.pdf (705.39KB; 3 download)
Ketersediaan
  • Perpustakaan FK
    • Nomor Panggil: KTI-FK-41
    • Non-tandon: 1 (dapat dipinjam: 0)
    • Tandon: tidak ada
    Lihat Detail Induk
Abstract
BACKGROUND : Cervical Cancer was ranked as number five cancer in the world that usually diagnosed in women. The primary etiology of cervical cancer is human papillomavirus infection. HPV vaccine was found at 2006. This vaccine can give protection against HPV infection. Many research stated that HPV vaccine was effective for women that has not have sexual intercourse. However, there is a problem that still hasn’t answered about the effectivity of HPV vaccine for women that has had sexual intercourse.
PURPOSE : To understand the effectivity of HPV bivalent vaccine for prevention against cervical cancer in women that has had sexual intercourse and women that has not have sexual intercourse.
METHOD : Using the literature review method with systematic review and summarizes the result from a few researches that related with vaccine effectivity that measured by HPV DNA status, HPV antibody serology, and cervix epithelium abnormalities. RESULT : After given the vaccine and monitored in ongoing research, for the women that has not have sexual intercourse, 4.7 % samples was detected HPV DNA positive and 29.8 % samples was having epithelial cervical abnormality. While the women that has had sexual intercourse, 51.2 % samples was found HPV DNA positive and 69.6 % samples was having epithelial cervical abnormality. HPV vaccine effectivity was about 95.3 % for women that has not have sexual intercourse and only about 49.8 % for women that has had sexual intercourse.
CONCLUSION : HPV bivalent vaccine was less effective in preventing HPV infection for women that has had sexual intercourse with positive HPV DNA status or abnormal cervical cytology test before they were given the vaccine compared to women that has not have sexual intercourse with negative HPV DNA status or normal cervical cytology.
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