Anda belum login :: 21 Jul 2024 16:40 WIB
ArtikelFructose and glucose co-ingestion during prolonged exercise increases lactate and glucose fluxes and oxidation compared with an equimolar intake of glucose  
Oleh: Lecoultre, Virgile ; Benoit, Rachel ; Carrel, Guillaume ; Schutz, Yves ; Millet, Gregoire P ; Schneiter, Philippe
Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The American Journal of Clinical Nutrition vol. 92 no. 05 (Nov. 2010), page 1071-1079.
Topik: Carbohydrate metabolism; Diabetes
Fulltext: Am J Clin Nutr-2010-Lecoultre-1071-9.pdf (166.9KB)
  • Perpustakaan FK
    • Nomor Panggil: A07.K.2010.02
    • Non-tandon: 1 (dapat dipinjam: 0)
    • Tandon: tidak ada
    Lihat Detail Induk
Isi artikelBackground: When fructose is ingested together with glucose (GLUFRU) during exercise, plasma lactate and exogenous carbohydrate oxidation rates are higher than with glucose alone. Objective: The objective was to investigate to what extent GLUFRU increased lactate kinetics and oxidation rate and gluconeogenesis from lactate (GNGL) and from fructose (GNGF). Design: Seven endurance-trained men performed 120 min of exercise at ˜60% GraphicO2max (maximal oxygen consumption) while ingesting 1.2 g glucose/min + 0.8 g of either glucose or fructose/min (GLUFRU). In 2 trials, the effects of glucose and GLUFRU on lactate and glucose kinetics were investigated with glucose and lactate tracers. In a third trial, labeled fructose was added to GLUFRU to assess fructose disposal. Results: In GLUFRU, lactate appearance (120 ± 6 µmol · kg-1 · min-1), lactate disappearance (121 ± 7 µmol · kg-1 · min-1), and oxidation (127 ± 12 µmol · kg-1 · min-1) rates increased significantly (P < 0.001) in comparison with glucose alone (94 ± 16, 95 ± 16, and 97 ± 16 µmol · kg-1 · min-1, respectively). GNGL was negligible in both conditions. In GLUFRU, GNGF and exogenous fructose oxidation increased with time and leveled off at 18.8 ± 3.7 and 38 ± 4 µmol · kg-1 · min-1, respectively, at 100 min. Plasma glucose appearance rate was significantly higher (P < 0.01) in GLUFRU (91 ± 6 µmol · kg-1 · min-1) than in glucose alone (82 ± 9 µmol · kg-1 · min-1). Carbohydrate oxidation rate was higher (P < 0.05) in GLUFRU. Conclusions: Fructose increased total carbohydrate oxidation, lactate production and oxidation, and GNGF. Fructose oxidation was explained equally by fructose-derived lactate and glucose oxidation, most likely in skeletal and cardiac muscle.
Opini AndaKlik untuk menuliskan opini Anda tentang koleksi ini!

Process time: 0.015625 second(s)