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The Capsule and Colorectal-Cancer Screening — The Crux of the Matter
Article from Journal - ilmiah internasional
The New England Journal of Medicine (keterangan: ada di Proquest) vol. 361 no. 03 (Jul. 2009)
page 300-301 .
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n the United States and other countries, colonoscopy has emerged as the primary screening test for colorectal cancer. Colonoscopy is believed to prevent colorectal cancer because polyps are removed during the procedure, but randomized trials have not been conducted to show this benefit. Because colonoscopy is an invasive, uncomfortable procedure, with a small but finite risk of complications, there is a demand for less invasive techniques. Imagine a small capsule with a built-in camera, the size of a tablet, that is easily swallowed and can detect cancer and polyps in your large bowel. It causes no discomfort while it travels through your colon taking photographs before being excreted with the stool. Yes, the colon capsule has been engineered and marketed and is in clinical use in Europe. However, the device's ability to detect cancer and polyps is not established. In this issue of the Journal, Van Gossum et al. report the findings of a European multicenter study comparing capsule endoscopy of the colon with standard colonoscopy for the detection of colorectal polyps and cancer.1 The study included 320 patients with abnormal findings at previous diagnostic procedures or with symptoms suggestive of colorectal cancer or polyps. Capsule endoscopy was followed by conventional colonoscopy.
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