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ArtikelVitamins and Perinatal Outcomes among HIV-Negative Women in Tanzania  
Oleh: Fawzi, Wafaie W. ; Msamanga, Gernard I. ; Urassa, Willy ; Hertzmark, Ellen ; Petraro, Paul ; Willett, Walter C. ; Spiegelman, Donna
Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The New England Journal of Medicine (keterangan: ada di Proquest) vol. 356 no. 14 (Apr. 2007), page 1423.
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  • Perpustakaan FK
    • Nomor Panggil: N08.K.2007.02
    • Non-tandon: 1 (dapat dipinjam: 0)
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Isi artikelBACKGROUND Prematurity and low birth weight are associated with high perinatal and infant mortality, especially in developing countries. Maternal micronutrient deficiencies may contribute to these adverse outcomes. METHODS In a double-blind trial in Dar es Salaam, Tanzania, we randomly assigned 8468 pregnant women (gestational age of fetus, 12 to 27 weeks) who were negative for human I immunodeficiency virus infection to receive daily multivitamins (including multiples I of the recommended dietary allowance) or placebo. All the women received prenatal; supplemental iron and folic acid. The primary outcomes were low birth weight I «2500 g), prematurity, and fetal death. RESULT The incidence of low birth weight was 7.8% among the infants in the multivitamin group and 9.4% among those in the placebo group (relative risk, 0.82; 95% confidence interval [CI], 0.70 to 0.95; P=0.01). The mean difference in birth weight between the groups was modest (67 g, P
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