A chromatin link that couples cell division to root epidermis patterning in Arabidopsis  

Oleh:

Caro, Elena ; Castellano, M. Mar ; Gutierrez, Crisanto

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: NATURE (keterangan: ada di Proquest) vol. 447 no. 7141 (May 2007), page 213.

Ketersediaan

Perpustakaan FK Nomor Panggil: N01.K.2007.05 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Cell proliferation and cell fate decisions are strictly coupled processes during plant embryogenesis and organogenesisI-s. In the Arabidopsis thaliana root epidermis, expression of the homeobox GLABRA2 (GL2) gene determines hair/non-hair cell fate6.7. This requires signalling of positional information from the underlying cortical layer8.9, complex transcriptional reguiation1o.1I and a change in chromatin accessibilityI2. However, the molecular connections among these factors and with cell division are not known. Here we have identified a GL2-expression modulator, GEM, as an interactor of CDTI, a DNA replication protein. GEM also interacts with TTGI (TRANSPARENT TESTA GLABRAI), a WD40-repeat protein involved in GL2-dependent cell fate decision, and modulates both cell division and GL2 expression. Here we show that GEM participates in the maintenance of the repressor histone H3K9 methylation status of root patterning genes, providing a link between cell division, fate and differentiation during Arabidopsis root development.

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