Detail Specialized Inhibitory Synaptic Actions Between Nearby Neocortical Pyramidal Neurons   Oleh:  Ren, Ming ; Yoshimura, Yumiko ; Takada, Naoki ; Horibe, Shoko ; Komatsu, Yukio Jenis: Article from Bulletin/Magazine Dalam koleksi: SCIENCE (keterangan: ada di Proquest) vol. 316 no. 5825 (May 2007), page 758. Topik: Neuroscience Ketersediaan Perpustakaan FK Nomor Panggil: S01.K.2007.05 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada     Lihat Detail Induk Isi artikel We found that, in the mouse visual cortex, action potentials generated in a single layer-2/3 pyramidal (excitatory) neuron can reliably evoke large, constant-latency inhibitory postsynaptic currents in other nearby pyramidal cells. This effect is mediated by axo-axonic ionotropic glutamate receptor-mediated excitation of the nerve terminals of inhibitory interneurons, which connect to the target pyramidal cells. Therefore, individual cortical excitatory neurons can generate inhibition independently from the somatic firing of inhibitory interneurons. Opini Anda Klik untuk menuliskan opini Anda tentang koleksi ini! Kembali

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