Prevalensi defisiensi Glucose-6-Phosphate Dehydrogenase (G6PD) pada anak Sekolah Dasar yang tinggal di daerah endemiS'malaria di Sulawesi utara  

Oleh:

Josef S.B. ; Kepel, Billy ; Nakatsu, Masami ; Matsuoka, Hiroyuki

Jenis: Article from Journal - ilmiah nasional - tidak terakreditasi DIKTI
Dalam koleksi: Jurnal Kedokteran YARSI vol. 15 no. 01 (Jan. 2007), page 059.
Topik: G6PD deficiency; malaria endemic; assay kit

Ketersediaan

Perpustakaan PKPM Nomor Panggil: J51 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada	Lihat Detail Induk
Perpustakaan FK Nomor Panggil: J26.K.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada	Lihat Detail Induk

Isi artikel

DeficienC1} of glucose-6-phosphate dehydrogenase (G6PD) is the most common enzyme disorder in . the world with a very high incidence in the tropics and sub-tropics as a result of malaria selection. North Sulawesi is a part of Indonesian archipelago where malaria has been endemic. This study was aimed to examine the prevalence of G6PD deficiency in the region. An observational cross sectional ,study was conducted on primary school students belong to different ethnic groups. The purposive sampling method was used to select 442 study subjects, age 5-9 years. The G6PDdeficiency. screening test was carried out using G6PD-assay kit. The prevalences of G6PD . deficiency male students were 0% in the.Minahasans, 7,4%-12,0% in the Sangihenese, and 4,0%10,3 % in the Bolaang-Mongondownese. The re~ults suggest that the highest prevalence of G6PD deficiency was in the Sa,ngihe ethnic group. Further molecular analysis would be beneficial to study the genetic relationship of those populations :-oith other neighboring population.

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