Juvenile Dermatomyositis: Pathophysiology and Disease Expression  

Oleh:

Pachman, Lauren M.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Pediatric Clinics of North America vol. 42 no. 05 (Oct. 1995), page 1071.

Ketersediaan

Perpustakaan FK Nomor Panggil: P13.K.1995.05 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Juvenile dermatomyositis is genetically restricted, immunologically mediated vasculitic connective tissue disease in which the skin and muscle are the primary areas of insult. The myositis is focal as documented by magnetic resonance imaging, and an unguided electromyogram or muscle biopsy may sample unaffected areas. Early institution of appropriate therapy is associated with less calcinosis, which is one consequence of disease severity and duration. Another component of active disease is osteopenia and the administration of a vitamin D supplement and a calcium sufficient diet may aid bone matrix repair. Newer modalities of therapy have been associated with shortened disease duration and less morbidity.

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