Rhabdomyolysis in Childhood: A Primer on Normal Muscle Function and Selected Metabolic Myopathies Characterized by Disordered Energy Production  

Oleh:

Carballo, Enrique Chaves

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Pediatric Clinics of North America vol. 39 no. 04 (Aug. 1992), page 821.

Ketersediaan

Perpustakaan FK Nomor Panggil: P13.K.1992.04 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Muscle disease in children is often heralded by evidence of rhabdomyolysis (the breakdown of skeletal muscle cells with liberation of their contents into the circulation). Rhabdomyolysis may be a chronic process or may present as a potentially life-threatening episode. In those children who do not have one of the muscular dystrophies, there are a wide variety of possible causes for rhabdomyolysis, including trauma, inflammation, toxic exposure, or various genetic defects in muscle energy metabolism, including deficiencies of enzymes involved in glycogenolysis, glycolysis, fatty acid oxidation, purine nucleotide metabolism, or mitochondrial respiration.

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