Acute Lymphoblastic Leukemia  

Oleh:

Pui, Ching-Hon

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Pediatric Clinics of North America vol. 44 no. 04 (Aug. 1997), page 831.

Ketersediaan

Perpustakaan FK Nomor Panggil: P13.K.1997.04 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Continued evolution of therapy for acute lymphoblastic leukemia has boosted cure rates from less than 50% in the 1970s to 66% or higher in the 1990s. This remarkable success has focused attention on the serious late sequelae of treatment and the small subsets of high-risk cases that have, so far, proved resistant to therapeutic intervention. The most promising leads to improved clinical management of childhood leukemia patients have come from molecular dissection of cases to recognize new disease categories and sensitive, highly specific targets for alternative therapies. The challenge for the future is to integrate emerging genetic information with historically sound clinical practices to ensure that patients are neither undertreated, leading to an unacceptably high relapse rate, nor overtreated, leading to debilitating late effects.

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