Detail A Network Thermodynamic Model of Kidney Perfusion With A Cryoprotective Agent   Oleh:  Diller, K. R. ; Lachenbruch, C. A. Jenis: Article from Bulletin/Magazine Dalam koleksi: Journal of Biomechanical Engineering vol. 121 no. 6 (1999), page 574-583. Topik: networks; network thermodynamic; kidney perfusion; cryoprotective agen Ketersediaan Perpustakaan Pusat (Semanggi) Nomor Panggil: JJ52.1 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada     Lihat Detail Induk Isi artikel A network thermodynamic model has been devised to describe the coupled movement of water and a permeable additive within a kidney during perfusion under the combined action of diffusive, hydrodynamic, and mechanical processes. The model has been validated by simulating perfusions with Me2SO, glycerol, and sucrose and comparing predicted weight and vascular resistance with experimental results obtained by Pegg (1993). The flows of CPA, water, colloid, and cellular impermeants are governed by a combination of the individual osmotic potential and pressure differences between compartments of the kidney, the viscoelastic behaviour of the tissue, and the momentum transferred between the flows. The model developed in this study presents an analytical tool for understanding the dynamics of the perfused kidney system and for modifying perfusion protocols to minimize the changes in cell volume, internal pressure build - up, and increases in vascular resistance that currently present barriers to the successful perfusion of organs. Opini Anda Klik untuk menuliskan opini Anda tentang koleksi ini! Kembali

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