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ArtikelKarsinoma Prostat: Temuan Patologik dan Implikasi Kliniknya  
Oleh: Suryawinata, Kidyarto
Jenis: Article from Journal - ilmiah nasional - tidak terakreditasi DIKTI - atma jaya
Dalam koleksi: Majalah Kedokteran Damianus vol. 05 no. 03 (Sep. 2006), page 161-169.
Topik: DISEASE; Prostatic Cancer; Adenocarcinoma; Gleason Grading; Diagnostic; Treatment
Fulltext: D01 v5 n3 p161 kelik2023.pdf (561.74KB)
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Isi artikelProstatic cancer is predominantly a disease of elderly and as the proportion of older men in the population increases so the incidence of prostatic carcinoma also increases. The cause of prostatic cancer is unknown, but several risk factors have been noted such as age, race, family history, hormonal and diet. Most prostatic cancers are adenocarcinomas and 710% arise in the peripheral zone. The most commonly system used for grading the histology is the gleason grading system which estimates the grade of prostatic cancer according to its differentiation. Gleason score is the sum of the two prominent grades Gleason score correlates with clinical prognosis. A needle biopsy is generally performed when prostatic cancer is suspected because of an abnormal digital rectal examination, an elevated serum of prostate specific antigen (PSA) level, or both. The diagnosis of prostatic cancer ultimately relies on pathological assessment of biopsy specimens provided by the pathologist. Protastic cancer is treated by surgey (radical prostatectomy), radiotherapy and hormonal manipulation depending on the stage of cancer, condition and age of the patient.
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