Discovering DNA Regulatory Elements With Bacteria  

Oleh:

Bulyk, Martha L.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Nature Biotechnology: The Science and Business of Biotechnology vol. 23 no. 8 (Agu. 2005), page 942-944.
Topik: dna; DNA; bacteris

Ketersediaan

Perpustakaan Pusat (Semanggi) Nomor Panggil: NN9.4 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

A bacterial one hybrid selection system offers a low tech alter native for determining the DNA binding specifities of transcription factors. Following nearly decade's worth of genomescale gene expression profiling and the more recent sequencing of multiple higher eukarytotic genomes, attention now shifting towards determining the regulatory mechanisms underlying gene expression patterns. A major obstacle in understanding transcriptional regulatory networks has been a lack of data on the DNA binsing specificaties of most transcription factors...

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