Turning Aptamers into Anticoagulants  

Oleh:

Famulok, Michael

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Nature Biotechnology: The Science and Business of Biotechnology vol. 22 no. 11 (Nov. 2004), page 1373-1374.
Topik: rna; aptamers; anticoagulants

Ketersediaan

Perpustakaan Pusat (Semanggi) Nomor Panggil: NN9.3 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

An RNA based anticoagulant and antidote are effective at controlling blood coagulation in animals. Blood coagulation involves a delicate balancing act. It must occur immediately in response to trauma to avoid blood oss, yet it would be fatal if it occurred in an uncontrolled fashion. Accordingly, drugs that modulate blood coagulation should allow exquisite control of this vital process. But existing anticoagulant drugs are relatively crude, with excessive bleeding a common side effect ...

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