Custom Design of Metabolism  

Oleh:

Liao, James C.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Nature Biotechnology: The Science and Business of Biotechnology vol. 22 no. 7 (Jul. 2004), page 823.
Topik: metabolism; custom design; metabolism

Ketersediaan

Perpustakaan Pusat (Semanggi) Nomor Panggil: NN9.1 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Two new approaches, RNA-enzyme fusions immobilized onto a surface and artificial RNA switches, could transform metabolic pathway engineering. Metabolic engineering requires both robust approaches to predicting and testing the outcomes of possible pathway manipulatins and reliable control mechanisms to subsequently allow the fine tuning of those pathways. Two papers, one recently published in science and the other in this issue, report progress on both fronts. In the first, Jung and Stephanopoulos use DNA molecules to capture difefrent RNA-enzyme fusions from a specific biochemical pathway in a 96-well microtiter plate assay...

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