Taurocholate Deconjugation and Cholesterol Binding by Indigeneous Dadih Lactic Acid Bacteria  

Oleh:

Ali, Muhammad ; Pato, Usman ; Parlindungan, Abdul K.

Jenis: Article from Journal - ilmiah nasional - terakreditasi DIKTI
Dalam koleksi: Hayati Journal of Biosciences vol. 12 no. 3 (Sep. 2005), page 103-107.
Topik: cholesterol; Cholesterol Binding
Fulltext: 49.pdf (35.66KB)

Ketersediaan

Perpustakaan Pusat (Semanggi) Nomor Panggil: HH13.7 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

High serum cholesterol levels have been associated with an increased risk for human coronary heart disease. Lowering of serum cholesterol has been suggested to prevent the heart disease. To reduce serum cholesterol levels one may consumed diet supplementat of fermented diary product such as dadih. Lactic acid bacteria present in dadih may alter serum cholesterol by directly bind to dietary cholesterol and/or deconjugation of bile salts. Acid and bile tolerance, deconjugation of sodium taurocholate, and the cholesterol-binding ability of lactic acid bacteria from daih were examined. Among ten dadih lactic acid bacteria tested, six trains namely I-11, I-2775, K-5, I-6257, IS-7257, and B-4 could bind cholesterol and deconjugate sodium taurocholate. However, the last four strains were very sensitive to bile. Therefore, Lactobacills fermentum I-11 and Leuconostoc lactis subsp. lactis I-2775 those were tolerant to acid and oxgall (bile) and deconjugate sodium taurocholate and bound cholesterol could be recomended as probiotic to prevent coronary heart disease.

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