The Effect of Adverse Intra uterine and Newborn Environments on Cognitive Development : The Experiences of Premature Delivery and Diabetes During Pregnancy  

Oleh:

Georgieff, Michael K. ; Sesma, Heather Whitney

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Development and Psychopathology vol. 15 no. 4 (2003), page 991-1016.
Topik: pregnancy; diabetes during pregnancy; cognitive development; newborn environments; premature delivery; adverse intra uterine
Fulltext: DD21_15_04_HEATHER WHITNEY SESMA.pdf (173.11KB)

Ketersediaan

Perpustakaan Pusat (Semanggi) Nomor Panggil: DD21.7 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

The prenatal and early postnatal periods constitute a time of rapid development when the brain is in a state of both heightened plasticity and vulnerability. Premature infants and infants of diabetic mothers represent two experiments of nature that allow researchers to observe how the developing brain responds to early biological challenge of either a global or regionally specific nature. We outline a set of organizing principles for conceptualizing the mechanisms by which early adverse experience may be encoded in the brain and subsequently expressed in behavior. We then review the available literature on developmental outcomes for infants born premature and infants of diabetic mothers. Research examining the relative influence of experience and maturation in the development of preterm infants indicates that advance experience does not accelerate the advent of specific cognitive capacities, but may enhance performance once the particular ability has emerged. Long - term follow - up of preterm infants also reveals evidence for plasticity and cognitive improvement into early adolescence for later maturing executive functions. Finally we offer an integrated model for investigating cognitive outcomes in infants of diabetic mothers that incorporates data from animal, electrophysiological, and behavioural measures.

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