Erythroleukemia  

Oleh:

Tedja, Ailinda Theodora ; Wirawan, Riadi

Jenis: Article from Journal - ilmiah nasional - terakreditasi DIKTI
Dalam koleksi: Indonesian Journal of Clinical Pathology and Medical Laboratory vol. 23 no. 02 (Mar. 2017), page 197-202.
Topik: AML-M6; Erythroleukemia; Acute Erythroid Leukemia; Pure Erythroid Leukemia; Flow Cytometric Immunophenotypic
Fulltext: I01 v23 n2 p197 kelik2017.pdf (1.9MB)

Ketersediaan

Perpustakaan FK Nomor Panggil: I01.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

According to the 2008 World Health Organization (WHO) classification, acute erythroid leukemia is divided into 2 subtypes i.e. erythroleukemia and pure erythroid leukemia. The 2008 WHO classification recommended that the diagnosis of acute erythroid leukemia can be established only by bone marrow evaluation, based on erythroblast count, blast count, dyserythropoiesis and dysgranulopoiesis. Erythroleukemia is an uncommon type of Acute Myeloid Leukemia (AML), representing less than 5% cases of AML. Erythroleukemia mainly affects the adult population with male predominance. This is a case of a 42-year-old female with pancytopenia and bone marrow evaluation showing 67% erythroblasts of All Nucleated Cells (ANC) with prominent dyserythropoiesis and 25% blasts of Non-Erythroid Cells (NEC) with 35% dysgranulopoiesis. This result established the diagnosis of erythroleukemia (AML-M6) based on the 2008 WHO classification. Flow cytometric immunophenotypic analysis showed erythroid and myeloid components which supported the diagnosis of erythroleukemia. Actually, flow cytometric immunophenotypic analysis is not required to establish the diagnosis of erythroleukemia. However, Cytogenetic analysis is recommended to determine prognosis.

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