Fructosamine and Glycated Albumin in Patients with Type 1 Diabetes Mellitus during Ramadhan Fasting  

Oleh:

Yulina, Vinzy ; Soehita, Sidarti ; Faizi, Muhammad ; Budiono

Jenis: Article from Journal - ilmiah nasional - terakreditasi DIKTI
Dalam koleksi: Indonesian Journal of Clinical Pathology and Medical Laboratory vol. 23 no. 02 (Mar. 2017), page 167-171.
Topik: Fructosamine; Glycated Albumin; Type 1 Diabetes Mellitus Patients; Fasting Ramadhan
Fulltext: I01 v23 n2 p167 kelik2017.pdf (571.78KB)

Ketersediaan

Perpustakaan FK Nomor Panggil: I01.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Fasting Ramadhan may increase the risk of complications in type 1 Diabetes Mellitus (DM) patients, which can be prevented by good glycemic control. Examination fructosamine and glycated albumin is used to describe the average blood glucose level over the previous 2-3 weeks, so it is more suitable to be used to describe the glycemic control during Ramadhan fasting month (one month). The purpose of this study was to compare and prove the correlation between fructosamine level and glycated albumin level at before, middle, and the end of Ramadhan fasting month in type 1 DM patients in the Dr. Soetomo Hospital. This study used an observational analytical design in 13 type 1 DM 9–18 year-old patients fasting Ramadhan. Fructosamine level examination used nitroblutetrazolium (NBT) with Cobas Integra. Glycated albumin value is calculated as a percentage of glycated albumin levels (using the enzymatic method) from total serum albumin level (using bromcresol purple), with Proline R-910. Results were analyzed by paired t-test statistics and Pearson’s correlation. There were no significant differences between the mean of fructosamine level compared at middle and before (p=0.307), the end and before (p=0.249), middle and the end of Ramadhan fasting month (p=0.362). There were no significant differences between the mean of glycated albumin values compared at middle and before (p=0,478), the end and before (p=0.285), middle and the end of Ramadhan fasting month (p=0.247). There was a significant positive correlation between the fructosamine level and glycated albumin value at before (p=0.0001, r=0.952), middle (p=0.0001, r=0.948) and the end of Ramadhan fasting month (p=0.0001, r=0.963). Fructosamine level and glycated albumin can be used as parameters of glycemic control in patients with type 1 DM fasting Ramadhan.

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