The Agreement between Light Criteria and Serum Ascites Albumin Gradient for Distinguishing Transudate and Exudate  

Oleh:

Puspasari, Rike ; Lillah ; Efrida

Jenis: Article from Journal - ilmiah nasional - terakreditasi DIKTI
Dalam koleksi: Indonesian Journal of Clinical Pathology and Medical Laboratory vol. 23 no. 02 (Mar. 2017), page 138-140.
Topik: Light Criteria; Serum Ascites Albumin Gradient
Fulltext: I01 v23 n2 p138 kelik2017.pdf (277.86KB)

Ketersediaan

Perpustakaan FK Nomor Panggil: I01.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Ascites fluid transudate or exudate should be distinguished as the first step to determine the cause of the underlying ascites disease. Combining some biochemical parameters will increase the sensitivity and specificity to distinguish types of ascites. This study aimed to determine the agreement of Light criteria and Serum Ascites Albumin Gradient (SAAG) to differentiate transudate and exudate in ascites fluid. This analytical cross sectional study was performed on 24 patients with ascites in the Dr. M. Djamil Hospital Padang, in March to September 2016. The parameters examined were total protein (colorimetric Biuret method), albumin (colorimetric bromocresol green method) and lactate dehydrogenase (LDH) (enzymatic method). The results of each parameter were formulated into Light criteria and SAAG. Light criteria and SAAG agreement in distinguishing a transudate and exudate ascites fluid was determined by kappa test. The results were considered statistically significant if p was < 0.05. Characteristics of the subjects in this study were 13 males (54.2%) and 11 females (45.8%) with a range of 22-76 years. Light criteria could determine 9 ascites fluid exudates and 15 ascites fluid transudates and SAAG could determine 2 ascites fluid exudates and 22 ascites fluid transudates. There was sufficient agreement (kappa value=0.26) but not significant (p>0.05) between Light criteria and SAAG. This study showed no agreement between the Light criteria and SAAG in distinguishing transudate and exudate ascites fluid. Further studies are needed to determine the sensitivity and specificity of both tests.

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