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ArtikelPancreatic Cancer in 31 Years Old Patient With Normal Serum Amylase Level  
Oleh: Flora, Melda F. ; Raharjo, Budiono ; Arthamin, Maimun Z.
Jenis: Article from Journal - ilmiah nasional - terakreditasi DIKTI
Dalam koleksi: Indonesian Journal of Clinical Pathology and Medical Laboratory vol. 23 no. 01 (Nov. 2016), page 96-101.
Topik: Pancreatic Cancer; Young Adult; Smokers; Normal Serum Amylase Level
Fulltext: I01 v23 n1 p96 kelik2017.pdf (166.19KB)
Ketersediaan
  • Perpustakaan FK
    • Nomor Panggil: I01.K
    • Non-tandon: 1 (dapat dipinjam: 0)
    • Tandon: tidak ada
    Lihat Detail Induk
Isi artikelPancreatic cancer is a malignancy of cells in pancreatic tissue. Its incidence increase in age over 60 years. However, about 20% can occur in young adult. The pathogenesis of pancreatic cancer is still unclear. It has been known that genetic mutation and exogenous factor such as smoking are associated with pancreatic cell malignancies. This was a case of a 31 years old male smoker, with the chief complaint of epigastric pain, radiating to the back, accompanied by nausea, vomiting and decreased appetite. There were icteric, dim percussion and ronchi, abdominal distension and ascites. The laboratory findings: there were leukocytosis, thrombocytopenia, increased AST more than 10 times URL, conjugated hyperbilirubinemia, increased serum alkaline phosphatase (ALP), gamma glutamyl transferase (GGT) and lipase, whereas serum amylase was within normal range. There was also elevated CA19-9 level. On CT Scan and MRI found images of primary pancreatic cancer which had metastatic to the pleura and liver. Normal serum amylase level in patient because of onset of increasing and decreasing amylase level occur rapidly and when the examination was performed the level was decreased to normal level. Conclusion, pancreatic cancer can occur in young adult and amylase level may be within normal range in pancreatic cancer.
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