Diagnostic Value Of St2 in Patients with Acute Myocardial Infarction  

Oleh:

H, Priyanto ; J, Nugraha ; SP, Edijanto

Jenis: Article from Journal - ilmiah nasional - terakreditasi DIKTI
Dalam koleksi: Folia Medica Indonesiana vol. 51 no. 2 (2015), page 106-109.
Topik: ST2; cTn-T; AMI
Fulltext: download-fullpapers-fmia30b32276dfull.pdf (42.32KB)

Isi artikel

Acute Myocardial Infarction (AMI) is a major problem threatening Indonesia and many countries. Each year AMI patients are increasing. ST2 is a novel cardiac marker for diagnosis and prognosis of acute myocardial infarction. The purpose of this study is to seek the diagnostic value of serum ST2 in patients with AMI. This cross sectional study was conducted in 46 patients with main complaint of chest pain at the Emergency Department, Dr. Soetomo Hospital from 20 April to 20 July 2013. Sera were examined for ST2, and then the diagnostic value was determined using the clinical criteria of AMI according to the Universal Definition of Myocardial Infarction (2007) as the gold standard. The results of ST2 serum levels measurement showed a sensitivity of 83% and specificity of 70% at a cut-off value of ST2 16.64 ng/mL and AUC 0.878, p = 0.000. The concordance examination between using cTn-T levels and ST2 was 48.1%. A significance correlation was obtained with correlation coefficient r = 0.489, p = 0.001 between the levels of cTn-T and ST2. In result, ST2 serum levels can be used for screening to aid the diagnosis of AMI. There is a weak correlation and concordance between cTn-T with ST2. Further research is needed to determine the diagnostic value of ST2 for the detection of AMI. (FMI 2015;51:106-109)

Opini Anda

Klik untuk menuliskan opini Anda tentang koleksi ini!

Kembali