Should Progesterone on the Human Chorionic Gonadotropin Day Still be Measured?  

Oleh:

Martinez, Francisca ; Rodriguez, Ignacio ; Devesa, Marta ; Buxaderas, Rosario ; Gomez, Maria Jose ; Coroleu, Buenaventura

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 105 no. 01 (Jan. 2016), page 86-92.
Topik: Clinical Outcomes; Ovarian Stimulation; Pregnancy Rate; Progesterone Levels
Fulltext: F02 v105 n1 p86 kelik2016.pdf (486.85KB)

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Perpustakaan FK Nomor Panggil: F02.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Objective: To evaluate in our setting whether there is currently a level of P on the hCG day (P-hCG) predictive of no pregnancy. Design: Observational study of prospectively collected data of the P-hCG levels of stimulated IVF cycles. Setting: In vitro fertilization unit. Patient(s): All cycles of IVF/intracytoplasmic sperm injection with fresh embryo transfer performed between January 2009 and March 2014. Intervention(s): None. Main Outcome Measure(s): Pregnancy rate. Result(s): Clinical pregnancy rate per ET was 38.7% and live birth rate was 29.1%. The P-hCG concentration was positively correlated to E2 on the hCG day, and the number of oocytes was negatively correlated to age. Progesterone on hCG day was higher among agonist- compared with antagonist-treated patients (mean ± SD: 1.13 ± 0.69 ng/mL vs. 0.97 ± 0.50 ng/mL) and among recombinant FSH compared with recombinant FSH + hMG stimulation (mean ± SD: 1.11 ± 0.58 ng/mL vs. 0.94 ± 0.50 ng/mL). Pregnancy rate was positively associated with the number of oocytes. There was no correlation between P-hCG value and pregnancy rate, overall or according to the type of treatment. Conclusion(s): In our setting there is no P-hCG value differentiating a good from a poor cycle success rate.

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