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ArtikelCutaneous and Mucocutaneous Leishmaniasis: Clinical Perspectives  
Oleh: Handler, Marc Z. ; Patel, Parimal A. ; Kapila, Rajendra ; Al-Qubati, Yasin ; Schwartz, Robert A.
Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: JAAD: Journal of the American Academy of Dermatology (keterangan: ada di ClinicalKey) vol. 73 no. 06 (Dec. 2015), page 897-908.
Topik: Bat; Dog; Gerbil; Kala-Azar; Leishmaniasis; Parasitic Disorders; Protozoan Diseases; Rodents; Sandfly; Tropical Diseases; Ulcer
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    • Nomor Panggil: J15.K
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Isi artikelLeishmaniasis is endemic in 98 countries and territories, with 1.2 million new cases per year, making it a worldwide concern. The deadly visceral form is a leading cause of death from tropical parasitic infections, second only to malaria. Leishmaniasis appears to be increasing in many countries because of extended urbanization. The disease reservoir includes small mammals; parasite transmission occurs via bite of the female phlebotomine sandfly. Disease manifestations vary and largely depend upon the Leishmania species acquired. It may be first evident with a range of findings—from a localized cutaneous ulcer to diffuse painless dermal nodules—or, in the mucocutaneous form, ulceration of the oropharynx. In the potentially deadly visceral form, the internal organs and bone marrow are affected.
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