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ArtikelIndeks Aterogenik Plasma di Penyakit Diabetes Melitus Tipe 2  
Oleh: Betaubun, Amarensi M ; Nurahmi ; Bahrun, Uleng ; Pakasi, Ruland
Jenis: Article from Journal - ilmiah nasional - terakreditasi DIKTI
Dalam koleksi: Indonesian Journal of Clinical Pathology and Medical Laboratory vol. 22 no. 01 (Nov. 2015), page 82-86.
Topik: Indeks Aterogenik Plasma; Log (TG/K-HDL); Diabetes Melitus Tipe 2
Ketersediaan
  • Perpustakaan FK
    • Nomor Panggil: I01.K
    • Non-tandon: 1 (dapat dipinjam: 0)
    • Tandon: tidak ada
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Isi artikelAtherogenic Index of Plasma (AIP) as a new marker of atherogenicity and directly related to the risk of atherosclerosis, is a simple and inexpensive method to assess the severity of atherogenic dyslipidemia. 97% of adult patients with type 2 DM (T2DM) will have dyslipidemia including increased levels of TG, low HDL-C levels whereas LDL cholesterol levels had no effect. To determine the atherogenic index of plasma in controlled and uncontrolled T2DM. A Cross-sectional study was conducted on 72 controlled T2DM samples and 112 uncontrolled T2DM samples from Clinic of Endocrine and Methabolic dr Wahidin Sudirohusodo Hospital Makassar, starting from April-May 2013. Fasting glucose level, triglycerides, HDL-C and HbA1c determined using ABX Pentra 400 (colorimetric method). Data then analyzed with Mann Withney U test. Most of the samples are male, with the age range from 51-60 years old. Mean AIP is not so different between the two groups (0.51±0.28 and 0.55±0.28 respectively). Fasting glucose level, triglycerides, HDL-C in T2DM uncontrolled were higher than controlled. The atherogenic index of plasma of controlled T2DM group were 0.93 times lower than uncontrolled T2DM, Mann Withney U test showed that there were no significant correlation between both of group (p>0.05). Atherogenic index of plasma cannot be used to distinguish between controlled and uncontrolled T2DM.
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