Delirium Diagnosis Methodology Used in Research: A Survey-Based Study  

Oleh:

Neufeld, Karin J. ; Nelliot, Archana ; Inouye, Sharon K. ; Ely, E.Wesley ; Bienvenu, O. Joseph

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The American Journal of Geriatric Psychiatry (keterangan: ada di ClinicalKey) vol. 22 no. 12 (Dec. 2014), page 1513-1521.
Topik: Delirium; dementia; amnestic; cognitive disorders; reference standards; research design; data collection

Ketersediaan

Perpustakaan FK Nomor Panggil: A35.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Objective To describe methodology used to diagnose delirium in research studies evaluating delirium detection tools. Methods The authors used a survey to address reference rater methodology for delirium diagnosis, including rater characteristics, sources of patient information, and diagnostic process, completed via web or telephone interview according to respondent preference. Participants were authors of 39 studies included in three recent systematic reviews of delirium detection instruments in hospitalized patients. Results Authors from 85% (N = 33) of the 39 eligible studies responded to the survey. The median number of raters per study was 2.5 (interquartile range: 2–3); 79% were physicians. The raters' median duration of clinical experience with delirium diagnosis was 7 years (interquartile range: 4–10), with 5% having no prior clinical experience. Inter-rater reliability was evaluated in 70% of studies. Cognitive tests and delirium detection tools were used in the delirium reference rating process in 61% (N = 21) and 45% (N = 15) of studies, respectively, with 33% (N = 11) using both and 27% (N = 9) using neither. When patients were too drowsy or declined to participate in delirium evaluation, 70% of studies (N = 23) used all available information for delirium diagnosis, whereas 15% excluded such patients. Conclusion Significant variability exists in reference standard methods for delirium diagnosis in published research. Increasing standardization by documenting inter-rater reliability, using standardized cognitive and delirium detection tools, incorporating diagnostic expert consensus panels, and using all available information in patients declining or unable to participate with formal testing may help advance delirium research by increasing consistency of case detection and improving generalizability of research results.

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