An Open-Label Trial of Bromocriptine in Nonfluent Aphasia: A Qualitative Analysis of Word Storage and Retrieval  

Oleh:

Gold, Michael ; VanDam, Deborah ; Silliman, Elaine R.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Brain and Language (Full Text) vol. 74 no. 2 (2000), page 141-156.
Topik: aphasia; anomia; treatment; bromocriptine; dopamine; storage; retrieval
Fulltext: 74_02_Gold.pdf (63.24KB)

Isi artikel

Anomia is a commonly found in aphasia and has been attributed to a loss of representations (storage deficit) or to a loss of access to these representations (retrieval deficit). Bromocriptine, a dopamine agonist, was tested on four patients, two men and two women, with nonfluent aphasia. The patients were tested in an openlabel ABBA design using a stochastic model that measured the degree of storage and retrieval deficits. All patients showed significant improvements in word retrieval. Bromocriptine may be a useful adjunct in the treatment of selected patients with a nonfluent aphasia in which retrieval deficits play a major role.

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