Allergic Rhinitis  

Oleh:

Wheatley, Lisa M. ; Togias, Alkis

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The New England Journal of Medicine (keterangan: ada di Proquest) vol. 372 no. 05 (Jan. 2015), page 456-463.

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Perpustakaan FK Nomor Panggil: N08.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Allergic rhinitis is defined as symptoms of sneezing, nasal pruritus, airflow obstruction, and mostly clear nasal discharge caused by IgE-mediated reactions against inhaled allergens and involving mucosal inflammation driven by type 2 helper T (Th2) cells.1 Allergens of importance include seasonal pollens and molds, as well as perennial indoor allergens, such as dust mites, pets, pests, and some molds. The pattern of dominant allergens depends on the geographic region and the degree of urbanization, but the overall prevalence of sensitization to allergens does not vary across census tracts in the United States.2 Sensitization to inhaled allergens begins during the first year of life; sensitization to indoor allergens precedes sensitization to pollens. Because viral respiratory infections occur frequently in young children and produce similar symptoms, it is very difficult to diagnose allergic rhinitis in the first 2 or 3 years of life. The prevalence of allergic rhinitis peaks in the second to fourth decades of life and then gradually diminishes

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