Restoring Synaptic Connections in the Inner Ear after Noise Damage  

Oleh:

Cunningham, Lisa L. ; Tucci, Debara L.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The New England Journal of Medicine (keterangan: ada di Proquest) vol. 372 no. 02 (Jan. 2015), page 181-182.

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Perpustakaan FK Nomor Panggil: N08.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Fifteen percent of Americans 20 to 69 years of age have hearing loss caused by exposure to high levels of noise.1 Noise damage results in anatomical, physiological, and neurochemical changes to the auditory system that are thought to cause functional declines in hearing, tinnitus, and hyperacusis, all of which can contribute to difficulty understanding speech, especially in challenging listening environments.2 Experiments in mice indicate that even moderate noise exposures can result in permanent loss of synaptic contacts in the inner ear and reduced hearing function.3 A recent study by Wan and colleagues4 showed that these synaptic connections can be restored with some help from the surrounding glia-like supporting cells.

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