Improved picture naming in chronic aphasia after TMS to part of right Broca's area: An open-protocol study  

Oleh:

Naeser, Margaret A. ; Martin, Paula I. ; Nicholas, Marjorie ; Baker, Errol H. ; Seekins, Heidi ; Kobayashi, Masahito ; Theoret, Hugo ; Fregni, Felipe ; Maria-Tormos, Jose ; Kurland, Jacquie ; Doron, Karl W. ; Pascual-Leone, Alvaro

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Brain and Language (Full Text) vol. 93 no. 1 (2005), page 95-105.
Topik: Aphasia; TMS; Naming; Stroke rehabilitation
Fulltext: 93_01_Naeser.pdf (625.8KB)

Isi artikel

Functional imaging studies with nonfluent aphasia patients have observed ‘‘over-activation’’ in right (R) language homologues. This may represent a maladaptive strategy; suppression may result in language improvement. We applied slow, 1 Hz repetitive transcranial magnetic stimulation (rTMS) to an anterior portion of R Broca's homologue daily, for 10 days in four aphasia patients who were 5–11 years poststroke. Significant improvement was observed in picture naming at 2 months post-rTMS, with lasting benefit at 8 months in three patients. This preliminary, open trial suggests that rTMS may provide a novel treatment approach for aphasia by possibly modulating the distributed, bi-hemispheric language network.

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