The association of macro- and microstructure of the corpus callosum and language lateralisation  

Oleh:

Westerhausen, Rene ; Kreuder, Frank ; Sequeira, Sarah Dos Santos ; Walter, Christof ; Woerner, Wolfgang ; Wittling, Ralf Arne ; Schweiger, Elisabeth ; Wittling, Werner

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Brain and Language (Full Text) vol. 97 no. 1 (2006), page 80-90.
Topik: Corpus callosum; Laterality; Language; Verbal fluency; fMRI; Diffusion-tensor imaging; Anisotropy; Mean diffusion; Handedness; Sex
Fulltext: 97_01_Westerhausen.pdf (409.08KB)

Isi artikel

The present study aimed to examine how differences in functional lateralisation of language are related to interindividual variations in interhemispheric connectivity. Utilising an fMRI silent word-generation paradigm, 89 left- and right-handed subjects were subdivided into four lateralisation subgroups. Applying morphological and diffusion-tensor MRI, midsagittal cross-sectional area as well as quantitative measures of molecular diffusion (anisotropy, mean diffusion) of the corpus callosum were determined to assess interhemispheric connectivity. Statistical analyses revealed group differences in molecular diffusion but not in callosal size, which may be interpreted to reflect a stronger and/or faster interhemispheric connection in strongly left-lateralised subjects as compared to moderately left-lateralised, bilateral, or moderately right-lateralised subjects.

Opini Anda

Klik untuk menuliskan opini Anda tentang koleksi ini!

Kembali