Risk Factors of Obstructive Sleep Apnea Syndrome in Obese Early Adolescents: A Prediction Model Using Scoring System  

Oleh:

Supriyatno, Bambang ; Said, Mardjanis ; Hermani, Bambang ; Sjarif, Damayanti R. ; Sastroasmoro, Sudigdo

Jenis: Article from Journal - ilmiah nasional - terakreditasi DIKTI
Dalam koleksi: Acta Medica Indonesiana vol. 42 no. 3 (Jul. 2010), page 152-157.
Topik: obesity; adolescent; obstructive sleep apnea syndrome; adenoid; tonsil; hypertrophy
Fulltext: risk factors of obstructive.pdf (59.88KB)

Isi artikel

Aim: to obtain the OSAS prevalence and risk factors of OSAS in obese early adolescents and to create a scoring system based on risk factors for diagnosing OSAS. Methods: an observational study in Jakarta, November 2007 until December 2008 on obese adolescents aged 10-12 years with snoring. Subjects underwent clinical examination, lung function test, paranasal sinus X-ray, and polisomnography. Measured outcomes were diagnosis of OSAS; sensitivity, specificity, predictive values, and likelihood ratios of a scoring system based on risk factors. Results: the prevalence of OSAS in obese early adolescents is 38.2% using AHI cut-off point of >3 on PSG. Tonsillar hypertrophy, adenoid hypertrophy, and neck circumference were the main risk factors. Scoring system was designed based on these results: OS= T + A + NC; OS= OSAS score; T= tonsil hypertrophy (>T3 scored 1,0.8 scored 1.5, <0.8 scored 0); NC = neck circumference (> 34 cm scored 1; <34 cm scored 0). Children were most likely to have OSAS if they had a total score of 3.5. This scoring system has a sensitivity of 62% (95%CI 47 to 77%), specificity 100% (95%CI 100 to 100%), positive predictive value 100% (95%CI 100 to 100%), negative predictive value 81% (95%CI 73 to 89%), unlimited LR(+), LR(-) of 0.38 (CI 95% 0.6 to 0.56). Conclusion: a scoring system based on tonsillar hypertrophy, adenoid hypertrophy, and neck circumference has sensitivity and specificity of 62% and 100% in diagnosing OSAS.

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