Estrogen-suppressed in vitro maturation: a novel approach to in vitro maturation  

Oleh:

Vitek, Wendy S. ; Witmyer, Jeannine ; Carson, Sandra A. ; Robins, Jared C.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Fertility and Sterility (keterangan: ada di ClinicalKey) vol. 99 no. 07 (Jun. 2013), page 1886-1890.
Topik: In vitro maturation; immature oocytes; polycystic ovarian syndrome

Ketersediaan

Perpustakaan FK Nomor Panggil: F02.K.2013.04 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Objective To evaluate the laboratory and clinical outcomes of estrogen-suppressed in vitro maturation (ES-IVM), a novel IVM protocol that eliminates the need for FSH stimulation and cycle monitoring. Design Case series. Setting Academic infertility center. Patient(s) Eighteen infertile couples undergoing ES-IVM (n = 20). Eligible candidates included women =38 years old with either polycystic ovarian syndrome, antral follicle count =15, and/or history of ovarian hyperstimulation syndrome. Intervention(s) ES-IVM. Main Outcomes Measure(s) Oocyte yield, maturation, fertilization, embryo quality, implantation, clinical pregnancy, and live-birth rate were analyzed. Result(s) The average number of oocytes retrieved was 16.7 ± 5.9, with a 52.1% maturation rate and a 58% fertilization rate by intracytoplasmic sperm injection. The average number of embryos transferred was 2.85 ± 0.6. The implantation rate was 17.5%, the clinical pregnancy rate was 40%, and the live-birth rate was 40%. Conclusion(s) The efficiency of ES-IVM appears to be similar to natural cycle and low-stimulation IVM protocols with respect to laboratory and clinical outcomes, while eliminating the need for FSH stimulation and cycle monitoring.

Opini Anda

Klik untuk menuliskan opini Anda tentang koleksi ini!

Kembali