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Manipulating nucleosome disfavoring sequences allows fine-tune regulation of gene expression in yeast
Oleh:
Tali, Raveh-Sadka
;
Levo, Michal
;
Shabi, Uri
Jenis:
Article from Journal - ilmiah internasional
Dalam koleksi:
Nature Genetics vol. 44 no. 07 (Jul. 2012)
,
page 743 - 750.
Ketersediaan
Perpustakaan FK
Nomor Panggil:
N12.K.2012.01
Non-tandon:
1 (dapat dipinjam: 0)
Tandon:
tidak ada
Lihat Detail Induk
Isi artikel
Eran Segal and colleagues measure the promoter activities of 70 different constructed promoter variants and find that poly(dA:dT) tracts significantly affect transcriptional outcome. They suggest that this is mediated by altering nucleosome organization and that these sequences can be manipulated to fine tune regulation of gene expression.
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