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Drug Dependence; Cancer Medicine
Oleh:
[s.n]
Jenis:
Article from Bulletin/Magazine
Dalam koleksi:
The Economist (http://search.proquest.com/) vol. 407 no. 8831 (Apr. 2013)
,
page 77.
Topik:
Cancer
;
Cancer Therapies
;
Pharmaceutical Sciences
;
Medical Research
Ketersediaan
Perpustakaan Pusat (Semanggi)
Nomor Panggil:
EE29.76
Non-tandon:
1 (dapat dipinjam: 0)
Tandon:
tidak ada
Lihat Detail Induk
Isi artikel
Less is sometimes more. That was the message delivered this week by Meghna Das Thakur of the Novartis Institutes for Biomedical Research. If a cancer evolves resistance to the drug being used to treat it, withdrawing that drug can sometimes stop the cancer in its tracks as effectively as prescribing treatment in the first place. Oncologists have suspected this for a while. Dr Thakur has, however, proved it is true--at least in the specific case of malignant melanoma and a drug called vemurafenib. It was one of the first reasonably reliable treatments for metastised melanoma. The problem is that continual mutation within what little of the tumour remains usually throws up resistant cell lines, and so most patients see their tumours rebound between six and nine months later. Once that happens, little can be done. Or so it seemed. But Dr Thakur and her colleagues wondered if the apparently counter-intuitive approach of withdrawing treatment might have a positive effect.
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