Detail Frontiers in the etiology and treatment of preterm premature rupture of membrane : from molecular mechanisms to innovative therapeutic strategies Bibliografi Author: Ludan, Xu ; Tiantian, Yang ; Meiling, Wen ; Dawei, Wen ; Chaoyang, Jin ; Meiwen, An ; Li, Wang ; Yang, Liu ; Junmei, Fan Topik: Amniotic membrane particles; Cellular senescence; Fetal membrane repair; Hydrogel; Inflammation; Oxidative stress; Preterm premature rupture of membranes Bahasa: (EN )     Penerbit: Springer     Tempat Terbit: New York    Tahun Terbit: 2024     Jenis: Article - diterbitkan di jurnal ilmiah internasional Fulltext: Frontiers in the Etiology and Treatment of Preterm Premature Rupture.pdf (1.69MB; 1 download) Abstract Preterm premature rupture of membranes (pPROM) poses a significant threat to fetal viability and increases the risk for newborn morbidities. The perinatal period of preterm infants affected by pPROM is often characterized by higher rates of mortality and morbidity, with associated risks of cerebral palsy, developmental delays, compromised immune function, respiratory diseases, and sensory impairments. pPROM is believed to result from a variety of causes, including but not limited to microbially induced infections, stretching of fetal membranes, oxidative stress, inflammatory responses, and age-related changes in the fetal-placental interface. Maternal stress, nutritional deficiencies, and medically induced procedures such as fetoscopy are also considered potential contributing factors to pPROM. This comprehensive review explores the potential etiologies leading to pPROM, delves into the intricate molecular mechanisms through which these etiologies cause membrane ruptures, and provides a concise overview of diagnostic and treatment approaches for pPROM. Based on available therapeutic options, this review proposes and explores the possibilities of utilizing a novel composite hydrogel composed of amniotic membrane particles for repairing ruptured fetal membranes, thereby holding promise for its clinical application. Kajian editorial Article from : Reproductive Sciences (2024) 31:917–931 Opini Anda Klik untuk menuliskan opini Anda tentang koleksi ini! Lihat Sejarah Pengadaan  Konversi Metadata   Kembali

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