Detail Efficacy and safety of bisoprolol 5 mg plus amlodipine 5 mg in patients with hypertension uncontrolled on monotherapy with 5 mg of amlodipine, a phase III multicenter, randomized, double-blind, placebo-controlled clinical trial – the AMCOR study Bibliografi Author: Jedrusik, Piotr ; Placha, Grzegorz ; Gaciong, Zbigniew ; AMCOR Trial Investigators Topik: Bisoprolol; Amlodipine; Combination therapy; Hypertension; Antihypertensive effect; Safety Bahasa: (EN )     Penerbit: Routledge Taylor & Francis Group     Tempat Terbit: New York    Tahun Terbit: 2023     Jenis: Article - diterbitkan di jurnal ilmiah internasional Fulltext: Efficacy and safety of bisoprolol 5 mg plus amlodipine 5 mg.pdf (1.62MB; 0 download) Abstract Objective To evaluate the antihypertensive effect and safety of bisoprolol 5?mg (BISO5mg) and amlodipine 5?mg (AMLO5mg) combination in comparison to AMLO5mg in hypertensive subjects uncontrolled with AMLO5mg. Methods Phase III, prospective, randomized, double-blind, placebo-controlled, 8-week trial with parallel design (EudraCT Number: 2019-000751-13). Results 367 patients aged 57.58?±?14.62?years were randomized to BISO5mg once daily on top of AMLO5mg (n?=?181) or placebo on top of AMLO5mg (n?=?186). Systolic/diastolic blood pressure (SBP/DBP) in the bisoprolol-treated group was reduced by 7.2?±?12.74/3.95?±?8.85?mmHg at 4?weeks (both p? Conclusions Addition of bisoprolol to patients uncontrolled with amlodipine monotherapy significantly improves blood pressure control. We can expect additional 7.2/3.95?mmHg SBP/DBP lowering effect by adding bisoprolol 5?mg to amlodipine 5?mg. Kajian editorial Article from journal : Current medical research and opinion, 2023, VOL. 39, NO. 7, 939–946 Opini Anda Klik untuk menuliskan opini Anda tentang koleksi ini! Lihat Sejarah Pengadaan  Konversi Metadata   Kembali

Copyright © 2006, 2007 Unika Atma Jaya, all rights reserved