Detail ASSOCIATION BETWEEN FRACTIONAL EXHALED NITRIC OXIDE AND PEAK EXPIRATORY FLOW WITH ATOPIC DISEASE USING THE ISAAC QUESTIONNAIRE IN URBAN STUDENTS Bibliografi Author: Tahar, Jason Melvin ; Ali, Soegianto (Advisor); Kaisar, Maria Mardalena Martini (Advisor) Topik: FeNO; PEF; Atopic disease; ISAAC; Urban Students; Lung Health Bahasa: (EN )     Penerbit: Program Studi Sarjana Kedokteran - Fakultas Kedokteran dan Ilmu Kesehatan Unika Atma Jaya     Tempat Terbit: Jakarta    Tahun Terbit: 2025     Jenis: Theses - Karya Tulis Ilmiah Kedokteran (KTI-FK) - Registration of Karya Tulis Ilmiah Kedokteran Fulltext: Jason Melvin Tahar_RegKTI_2025.pdf (2.46MB; 1 download) Jason Melvin Tahar_LembarAdministrasi.pdf (945.06KB; 1 download) Abstract Introduction: Asthma is a growing public health concern among, particularly in urban regions such as Jakarta. The rising prevalence is driven by a complex interplay of environmental and genetic factors. While the use of fractional exhaled nitric oxide (FeNO) and peak expiratory flow (PEF) for asthma assessment are globally recognized, their applications in Indonesia’s clinical setting are still under-utilized. This study evaluated the association between FeNO and PEF measurements with atopic disease prevalence determined by ISAAC questionnaire, among urban students in Jakarta. Methods: This cross-sectional study surveyed data from 222 elementary students using the ISAAC questionnaire. Objective measurements using FeNO and PEF were conducted to capture airway inflammation and lung functions status. Comparison of objective markers between overall atopy, atopic diseases, and baseline characteristics were analyzed using Mann-Whitney U and Kruskal Wallis test. If variable were normally distributed, independent t-test were used. Spearman’s test used to assess correlation between FeNO and PEF. Results: The geometric mean (GM) of FeNO in this population was 17.73 ± 1.63 ppb, whereas 67 students (30.18%) were found to have elevated FeNO values (intermediate and high), while 47.75% of the students’ PEF value were below 80% of the highest PEF expected. Only 34.23% of students were not suspected of any atopic disease. Asthma, rhinitis and eczema were found to be prevalent, with the percentages of 14.41%, 58.11% and 13.96 % respectively. Comparison between overall atopic found height and weight to be significantly associated. When comparing isolated atopic diseases, only height were still associated. FeNO and PEF were associated when analyzed using Kruskal Wallis, while spearman test shows no significant correlation. Conclusion: Atopic disease (65.77%) , airway inflammation (30.18%) and airway obstruction (47.75%) were highly prevalent among urban students. FeNO and PEF were found to be weakly associated, highlighting the objective markers to be used complementary. Opini Anda Klik untuk menuliskan opini Anda tentang koleksi ini! Lihat Sejarah Pengadaan  Konversi Metadata   Kembali

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