Persalinan Pervaginam dan Menyusui sebagai Faktor Risiko Kejadian HIV pada Bayi  

Oleh:

Purnaningtyas, Dewi Astri ; Dewantiningrum, Julian

Jenis: Article from Journal - ilmiah nasional - terakreditasi DIKTI - non-atma jaya
Dalam koleksi: Media Medika Indonesiana vol. 45 no. 03 (Sep. 2011), page 139-143.
Topik: Vertical transmission HIV; CD4 concentration; mode of delivery; breastfeeding; ARV

Ketersediaan

Perpustakaan FK Nomor Panggil: M30.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Vaginal delivery and breastfeeding as risk factors of HIV in infants Background: HIV incidence is increasing among housewives, leading to increasing HIV in infants. The aim of this study was to identify risk factors of HIV in infants. Method: A case control study was carried out among women who visited VCT (voluntary counselling and testing) clinic RSUP Dr. Kariadi during 2003-2011 that fulfill the inclusion criteria of term delivery and babies infection confirmed by VCT or PCR DNA/RNA. Risk factors were assessed by interview about ARV consumption during pregnancy, mode of delivery, prophylactic ARV for neonates and breastfeeding. CD4 concentration before delivery was defined from medical report. All subject divided into two group based on HIV infected children status, HIV and non HIV. Analysis used bivariate analysis using Chi square and odd ratio. Result: From 28 women: 16 women in HIV group and 12 women in non HIV group. Breast feeding (OR 13.00; 95% CI 2.12-79.59, p=0.006) and vaginal delivery (OR 6.07; 95% CI 1.11-3.24, p=0.050) were the most important risk factors for HIV infection in infants. ARV consumption during pregnancy (OR 0.13; 95% CI 0.01-1.40), ARV prophylactic in neonates (OR 0.20; 95% CI 0.02- 2.23), CD4 >400 sel/mm3 before delivery (OR 0.33; 95% CI 0.03-4.019) were not risk factors. Conclusion: Vaginal delivery and breastfeeding were risk factor for the incidence of HIV-infected infants.

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