Metabolic risk factors of urinary stone disease in children  

Oleh:

Tanuwidjaja, Dandy ; Siregar, Safendra

Jenis: Article from Journal - ilmiah nasional - terakreditasi DIKTI
Dalam koleksi: Jurnal Urologi Indonesia (Indonesian Journal of Urology) vol. 19 no. 01 (Jan. 2012), page 29-33.
Topik: Urinary stone disease; children; metabolic risk factors.

Ketersediaan

Perpustakaan FK Nomor Panggil: J33.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Objective: To evaluate metabolic riskj'actor of urinary stone disease in children. Material & method: In this hospital-based preliminary study, children with urinary stone disease who underwent stone removal in Hasan Sadikin Hospiial were included. Control group consisted children with other diseases, matched for age and BMI. Blood evaluation (urn acid, calcium and phosphate) and 24-hour urine evaluation (calcium, phosphate, sodium, magnesium, uric acid, acidity, and urine volume) were measured!before the stone removal. Stone analysis was performed later. Data was analyzed using Kruskal Wallis and Spean tan correlation test. Results: Eight subjects with urinary tract stone and 8 normal subjects were included to the study. This study included 4 (50%) subjects with renal stone, 3 (37,5%) subjects with bladder stone, and I (12,5%) subject with distal urethral stone. Stone analysis revealed 6 (75%) calcium oxalate, I (12,5%) calcium phosphate, and 1 (12,5%) struvite stone. There was no significant difference in blood calcium, phosphate, and uric acid between groups. 24 hours urinary calcium level was higher in subjects with stone disease (40,8 mg vs 10,6 mg, p=0,027). Urinaiy calcium-to-creatinine ratio was also higher in stone disease (0,23 vs 0,02 mg/mg creatinine, p~0,002). There was no significant difference of other urinary electrolites and uric acid level between groups. Conclusion: Twenty four hours urinary < alcium level and urinary calcium-to-creatinine ratio is higher in children with urinary stone disease.

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