Difference in serum PSA level and IIEF-5 before and after turp in BPH patients without urinary retention  

Oleh:

Hasibuan, Zulfian ; Soetojo ; Djatisoesanto, Wahjoe ; Widodo JP.

Jenis: Article from Journal - ilmiah nasional - terakreditasi DIKTI
Dalam koleksi: Jurnal Urologi Indonesia (Indonesian Journal of Urology) vol. 19 no. 01 (Jan. 2012), page 42-48.
Topik: Prostate-specific antigen; benign prostatic hyperplasia; transurethral resection of the prostate; erectile dysfunction.

Ketersediaan

Perpustakaan FK Nomor Panggil: J33.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Objective: Determine change in serum prostate-specific antigen (PSA) and International Index of Erectile Function fHEF-5) following transurethral resection of the prostate (TURP). Material & Method: Eighteen men with age range of 50 - 69 years, were divided in two groups, group I 50-59 years (mean 56,5) and group II60-69 years (mean 67,2). Both groups underwent measurement of serum PSA and IIEF-5 pre-operative, and repeated at 30, 60, and 90 days after TURP. Results: Level of serum PSA after TURP is decreased in most patients after 30, 60, and 90 days (72%, 72% and 78%). Mean value of PSApre-operatively is 5,3 ±3,3 ng ml. After TURP, serum PSA level was 3,5 ±3,0ng/ml (30days); 2,9 ±2,9ng/ml (60 days) and 1,8 ± 1,3ng/ml (90 days). Pre-operative PSA level was significantly decreased in Group 1 during the 60 and 90 days post TURP, whilein Group II pre-operative PSA level was significantly decreased only in 90 days of observation. Overall there is no significant difference in PSA levels in both groups (p> 0,05). The decrease of PSA per gram resected in 30, 60, and 90 days were 0,10 ng/ml; 0,16 ng/ml and 0,24 ng/ml consecutively. There is no change in normal IIEF-5 score. Decrease of the IIEF-5 score in group I was measured at 30 days, but the score increased after 60 and 90 days. Meanwhile Group II showed decrease of IIEF-5 score. Pre-operative IIEF-5 score compared to the 30 days post TURP was significantly different but not significantly different compared n ith to score at 60 and 90 days. In Group I IIEF-5 score was significantly higher compared to Group II (p < 0,05). Prostatitis was found in 8 patients, but there is no difference in serum PSA level decrease between patients with or without prostatitis. Conclusion: There was a decrease in serum PSA after TURP in BPH patients with LUTS at every measurement at 30, 60, and 90 days. PSA level after TURP depends on various factors, including pre-operative PSA, pre-operative prostate volume and prostatevolume resected. Incidence ojerectile dysfunction post TURP was low.

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