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ArtikelDebugging the Problem; Malnutrition and the Microbiome  
Oleh: [s.n]
Jenis: Article from Bulletin/Magazine
Dalam koleksi: The Economist (http://search.proquest.com/) vol. 406 no. 8821 (Feb. 2013), page 69-70.
Topik: Malnutrition; Nutrition Research; Bacteria; Research
Ketersediaan
  • Perpustakaan Pusat (Semanggi)
    • Nomor Panggil: EE29.75
    • Non-tandon: 1 (dapat dipinjam: 0)
    • Tandon: tidak ada
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Isi artikelSometimes, the blindingly obvious is not actually correct. Malnutrition, for instance, is obviously caused by a lack of food. And yet, as a paper published in this week's Science by Jeffrey Gordon and his colleagues at Washington University, in St Louis, points out, that is not always a complete explanation. Dr Gordon's team have been looking at twins in Malawi. Two years ago they announced that despite both members of such pairs eating the same diet, one twin often remains healthy while the other becomes malnourished. This discordance is associated with differences in the gut bacteria of the individuals involved. Their latest paper explores why. The answer seems to lie partly in the role bacteria play in providing essential nutrients to the body and partly in the inhibition of a biochemical pathway called the Krebs cycle, which is at the core of every organism's metabolism. The Krebs cycle transfers the energy in sugar to a molecule called ATP, which is the body's energy currency. Interfere with it and the whole metabolism will slow down, with potentially catastrophic consequences. And if a child has the wrong bacteria in his gut, that seems to be what happens.
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