Detail Evidence that the M antigen of Histoplasma capsulatum var. capsulatum is a catalase which exhibits cross-reactivity with other dimorphic fungi Bibliografi Author: Hamilton, A. J. ; Bartholomew, M. A. ; Figueroa, J. ; Fenelon, L. E. ; Hay, R. J. Topik: M antigen; Histoplasma; Histoplasma capsulatum var. capsulatum; Dimorphic fungi; Monoclonal antibodies Bahasa: (EN )     Tahun Terbit: 1990     Jenis: Article - diterbitkan di jurnal ilmiah internasional Fulltext: Evidence that the M antigen of Histoplasma capsulatum.pdf (518.7KB; 2 download) Abstract A panel of monoclonal antibodies (Mabs) was raised against histoplasmin, the antigen derived from the mycelial phase of Histoplasma capsulatum var. capsulatum which contains the diagnostically useful H and M antigens. A number of Mabs were obtained which recognized a 70–75 kD component of an antigenic preparation of H. capsulatum var. capsulatum by Western blotting. When reacted with histoplasmin by Western blotting the Mabs recognized a similar 70–75 kD band, together with a series of higher molecular mass bands at approximately 130, 190 and 230 kD, a pattern which correlates strongly with both the published relative molecular mass (Mr) of the M antigen and the known subunit structure of the enzyme catalase. These Mabs were also shown to recognize a commercial preparation of Aspergillus niger catalase by ELISA. Other dimorphic fungi were also reactive with these Mabs by Western blotting, indicating the presence of common epitopes on the catalase molecules of these species. Kajian editorial Article from : Journal of Medical and Veterinary Mycology, Volume 28, Issue 6, November 1990, Pages 479–485 Opini Anda Klik untuk menuliskan opini Anda tentang koleksi ini! Lihat Sejarah Pengadaan  Konversi Metadata   Kembali

Copyright © 2006, 2007 Unika Atma Jaya, all rights reserved