Detail Pengujian Aktivitas Antioksidan Makro Alga Sumbawa Dalam Hubungannya Dengan Kandungan Senyawa Bioaktif Dan Efek Farmakologi (artikel Jurnal Riset Kesehatan Nasional Vol.6 No.2 2022) Bibliografi Author: Sianipar, Erlia Anggrainy ; Satriawan, Natasha ; Sumartono, Juliana ; Kambira, Pretty Falena Atmanda Topik: Macroalgae; antioxidant; Sumbawa; bioactive compounds; pharmacological effects; JABFUNG-FKIK-EAS-2023-03 Bahasa: (ID )     Penerbit: LPPM Institut dan Teknologi Kesehatan (ITEKES) Bali     Tempat Terbit: Denpasar, Bali    Tahun Terbit: 2022     Jenis: Article - diterbitkan di jurnal ilmiah nasional Fulltext: B3 Pengujian Aktivitas Antioksi.pdf (757.78KB; 1 download) [Informasi yang berkaitan dengan koleksi ini di internet] Abstract A popular natural resource of Sumbawa Island is macroalgae. Chlorophyta, Phaeophyta, and Rhodophyta are types of macroalgae that have been cultivated and utilized by the local community. However, its potential to treat many diseases is still under-explored. Based on the content of bioactive compounds, macroalgae is believed to have antioxidant activity that could scavenge free radicals and thus potentially prevent and treat various diseases caused by excessive free radicals. This study aimed to analyze the antioxidant activity of Sumbawa macroalgae in various solvent fractions. Samples were macerated in n-hexane, ethyl acetate, and ethanol solvents. Antioxidant activity was tested using 1,1-Diphenyl-2-picryl Hydrazil (DPPH) method and ascorbic acid as a positive control. The percentage yield of extracts from various solvent fractions varied between 0.25% to 0.62%. The result of antioxidant activity testing showed that the IC50 (Inhibition Concentration) value of macroalgae extract was moderate to weak in the range of 108.1 ± 1.068 to 665.2 ± 0.479 g/mL and positive control was 6.156 ug/mL ±0.563g/mL. The relationship between antioxidant activity and the content of bioactive compounds and their pharmacological effects were discussed in this study. This study concluded that the ethyl acetate fraction of macroalgae had higher antioxidant activity than the n-hexane and ethanol fractions. Further analysis was needed to determine the composition of the bioactive compounds and identify their pharmacological effects at the molecular level. Opini Anda Klik untuk menuliskan opini Anda tentang koleksi ini! Lihat Sejarah Pengadaan  Konversi Metadata   Kembali

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