Effects of red orange juice intake on endothelial function and inflammatory markers in adult subjects with increased cardiovascular risk  

Oleh:

Buscemi, Silvio ; Rosafio, Giuseppe ; Arcoleo, Gioacchina ; Mattina, Alessandro

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The American Journal of Clinical Nutrition vol. 95 no. 05 (May 2012), page 1089-1095 .
Topik: VITAMINS; Minerals; Phytochemicals

Ketersediaan

Perpustakaan FK Nomor Panggil: A07.K.2012.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Background: Oxidative and inflammatory stresses are involved in the pathogenesis of atherosclerosis. The consumption of fruit and vegetables is associated with improved health and reduced cardiovascular risk. Red oranges have a high content of antioxidant and antiinflammatory substances, but there is a paucity of data concerning their effects on cardiovascular biomarkers in subjects with increased cardiovascular risk. Objective: We investigated the effect of red orange juice intake on endothelial function, oxidative stress, and markers of inflammation in subjects with increased cardiovascular risk. Design: Nineteen nondiabetic subjects with increased cardiovascular risk (aged 27–56 y) were included in a randomized, placebo-controlled, single-blind crossover study and compared with 12 healthy, nonobese control subjects. In 2 periods of 7 d each with a 3-d interval, each participant alternatively received 500 mL red orange juice/d and 500 mL placebo/d in a random sequence. All measurements were performed in the morning after overnight fasting. Results: Endothelial function, which was measured as flow-mediated dilation, significantly improved and was normalized (5.7% compared with 7.9%; P < 0.005) after 1 wk of red orange juice consumption. Similarly, concentrations of high-sensitivity C-reactive protein, IL-6, and TNF-a significantly decreased (P < 0.001). Red orange juice had no significant effect on nitric oxide plasma concentrations. Conclusion: A 7-d consumption of red orange juice ameliorates endothelial function and reduces inflammation in nondiabetic subjects with increased cardiovascular risk.

Opini Anda

Klik untuk menuliskan opini Anda tentang koleksi ini!

Kembali