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A Combination of High-dose Vitamin C Plus Zinc for the Common Cold
Oleh:
Maggini, S.
;
Beveridge, S.
;
Suter, M.
Jenis:
Article from Journal - ilmiah internasional
Dalam koleksi:
The Journal of International Medical Research vol. 40 no. 01 (Jan. 2012)
,
page 28-42.
Topik:
Vitamin C
;
Zinc
;
Micronutrients
;
Common Cold
;
Respiratory Infections
;
Immune System
Ketersediaan
Perpustakaan FK
Nomor Panggil:
J11.K
Non-tandon:
1 (dapat dipinjam: 0)
Tandon:
tidak ada
Lihat Detail Induk
Isi artikel
Vitamin C and zinc play important roles in nutrition, immune defence and maintenance of health. Intake of both is often inadequate, even in affluent populations. The common cold continues to place a great burden on society in terms of suffering and economic loss. After an overview of the literature on the effects of the separate administration of either vitamin C or zinc against the common cold, this article presents data from two preliminary, double-blind, randomized, placebo-controlled trials, conducted with a combination of 1000 mg vitamin C plus 10 mg zinc in patients with the common cold. In both studies, a nonsignificant reduction of rhinorrhoea duration (range 9 - 27%) was seen. In pooled analyses of both studies (n = 94), vitamin C plus zinc was significantly more efficient than placebo at reducing rhinorrhoea over 5 days of treatment. Furthermore, symptom relief was quicker and the product was well tolerated. In view of the burden associated with the common cold, supplementation with vitamin C plus zinc may represent an efficacious measure, with a good safety profile, against this infectious viral disease.
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