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Correlation between APRI and HbA1C as a predictor of liver fibrosis (presented at The 9th Liver Update Jakarta, 20-22 May 2016)
Bibliografi
Author:
Adi Suhanto, Marcella
;
Steffanus, Mario
;
Tenggara, Riki
Topik:
APRI
;
diabetes
;
liver fibrosis
;
JABFUNG-FKIK-RTG-2021-20
Bahasa:
(EN )
Penerbit:
Divisi Hepatobiliary, Departemen of Internal Medicine, Fakultas Kedokteran, Universitas Indonesia dan Asosiasi Indonesia untuk Studi Hati (Ina ASL / PPHI)
Tempat Terbit:
Jakarta
Tahun Terbit:
2016
Jenis:
Poster - pada seminar nasional
Fulltext:
B-20 Dokumen.pdf
(1.62MB;
1 download
)
Abstract
Backround
Diabetes has been the most common cause of liver disease nowadays. By the increasing number of diabetes mellitus, concerning of liver fibrosis need to be detected more early. In Indonesia, screening for liver fibrosis is still expensive. APRI as a non-invasive marker for liver fibrosis might be an alternative tools for this.
Methods
This was a single-center cross sectional study carried out in 70 diabetic patients hospitalized at Atma Jaya Hospital from 2013 to 2015. APRI was used as the tool for screening liver fibrosis. HbA1C was used to determined control status of diabetes mellitus. Statistic analyses were performed using SPSS.15. Correlation was evaluated by the Spearman correlation coefficient.
Results
Seventy diabetic patients were enrolled for this study, 51% (36) was male. The mean age was 55.1 (1583). Numeric data was obtained (p<0.05, Kolmogorov Smirnov). By using 0.45 as the cut-off point of liver fibrosis, we found positive correlation between diabetic patients and liver fibrosis (r 0.28, p<0.05, SpearmanTest).
Conclusion
APRI seems to be a good non-invasive method for prediction of advanced liver fibrosis in diabetic patients.
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